Is My Progesterone Too Low for 15 Weeks Pregnant?

Question

I am 42 years old and 16 weeks pregnant. I have had four first trimester losses (before nine weeks). I am MTHFR compound hetero (C677 and 1298). I am on Lovenox, folgard, synthroid, progesterone suppositories 400, D3-1000, iron, and multivitamins. I asked my high risk doctor to test my progesterone levels and he refused. I was able to get it tested through another doctor and my levels at 15 weeks+4 days were 24.39. I am concerned that the number is low, especially with the 400 progesterone suppositories that I have been taking. I looked at various web sites and it shows the range for 2nd trimester to be either 17-50 or 25-90. I went back to my reproductive endocrinologist (RE) and he said to continue the suppositories. Do you think that my number is particularly low?
Thank you so much!

Answer

Last Updated: February 3, 2022
Your progesterone level is too low; it should be greater than 49 at 16 weeks. According to the NaProTechnology protocol (www. NaProTechnology.com), you should be on 200 mg of progesterone by intramuscular injection twice a week. Furthermore, unless you skipped the suppository the night before the blood test, your level might even be lower.

You can find a medical provider knowledgeable in progesterone use in pregnancy at https://www.fertilitycare.org/find-a-mc

In health,

George Delgado, M.D., F.A.A.F.P.

Answered By:

George Delgado, M.D., F.A.A.F.P.
President and Founder of Steno Institute and Medical Director of Culture of Life Family Services (COLFS), San Diego, is a Professional Member / Supporter of CANFP. Board certified in both family medicine and hospice and palliative medicine, Dr. Delgado received his medical degree from the University of California, Davis, and completed his residency at Santa Monica Hospital/UCLA. Dr. Delgado is a Natural Family Planning Medical Consultant, trained in NaProTechnology.

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