Is Prometrium Safe While Trying to Conceive?

Question

I am trying to conceive and I have been put on prometrium after the doctor established that I have low progesterone levels. My question is, is it safe to be on a pill form of progesterone while trying to conceive? Your web site seems to only prescribe intramuscular injections or vaginal gel.
Thanks,

Catherine

Answer

Last Updated: December 1, 2021
Dear Catherine,

As long as the pill contains progesterone and not an artificial progestin, then it is safe and can be effective at preventing miscarriages. Prometrium is a brand name for progesterone; feel confident taking it.

Progesterone is most effective when given by intramuscular injection because higher levels are achievable in the body. The second most effective is in sustained release vaginal suppository form because the vagina is a “direct route,” via blood vessels, to the uterus. Sustained release oral pills are next and Prometrium, which is immediate release micronized progesterone, the lowest.

Prometrium can cause sleepiness so it is usually dosed at night. The vaginal suppositories can cause vaginal dryness.

In health,

George Delgado, M.D., F.A.A.F.P.

Answered By:

George Delgado, M.D., F.A.A.F.P.
President and Founder of Steno Institute and Medical Director of Culture of Life Family Services (COLFS), San Diego, is a Professional Member / Supporter of CANFP. Board certified in both family medicine and hospice and palliative medicine, Dr. Delgado received his medical degree from the University of California, Davis, and completed his residency at Santa Monica Hospital/UCLA. Dr. Delgado is a Natural Family Planning Medical Consultant, trained in NaProTechnology.

Read more related questions

Panic About Fertility

I’m having a complete panic about my fertility. I’m 30 years old and stopped taking the pill a few months ago after being on it…

Trying to Conceive for First Time

I am a 38 year old woman, trying to conceive for the first time. I am using the Clearblue Fertility Monitor and it showed high…

Could Polyp Be Causing Miscarriage?

Could you please help me as I don’t know who I can ask? I am 43 years old (have had no children before) and within…

Breastfeeding and Miscarriage

I am a 38 year old woman with three children who has also had five miscarriages. I am currently four weeks pregnant (six weeks after…

Conflicting Advice on Progesterone and Infertility

I am 27 years old and my husband and I have been trying for our first child for five months. I have been charting since…

Low Estradiol on Day Three of Cycle

I am 26. I have had four miscarriages. Recently I had cycle day three labs done. The results are as follows: FSH 5.5 TSH 1.33…

Is My Premenstrual Spotting Related to My Miscarriages

I am 40 years old, with an almost-three-year-old daughter. My husband and I have been married for eight and a half years. We went through…

New Normal After Stillbirth?

My first child (a beautiful baby girl) was stillborn in February of this year (40 weeks gestation with no known cause). My husband and I…

Poor Cervical Mucus and Now Miscarried

I am 37 years old, with two children ages six and three and a half. I have been trying to conceive for one year using…

Still Think Something is Just Not Right

I am 26 years old and my husband and I have been practicing NFP since we married two years ago. Right after getting married, I…

What is Normal TSH?

I was having a difficult time becoming pregnant. I finally got pregnant, but then miscarried. This was unusual for me because I quickly became pregnant…

How Long Should I Wait to Conceive After Weaning

I had a miscarriage a few weeks ago, and I believe that it is very possible it was due to low hormone levels. I had…

Create An Account

This is not a membership, this is an account for our CANFP website. If you decide you would like to sign up for one of our memberships later, you can do so with or without this account.

First Name *
Last Name *
E-mail *
Username *
Password *
Confirm Password *
Edit Profile
Information
Subscriptions
Payments
Order History
Downloads
Shipping and Billing
Donations
Settings
Login Information
Notification Settings
Notification Subscriptions
Profile

CANFP conducts varied outreach programs to the community at large, in addition to serving our members (NFP users, teachers, and advocates).

CANFP provides education programs tailored to the audience, not only on Natural Family Planning, but on the wide variety of topics related to it.

Programs can be continuing education for NFP Professionals, introductory information for a lay audience of youth or adults new to the topic, or specifically tailored to the interests of a professional audience, such as educators, physicians, or clergy. Content is faith based or secular, whichever is suitable for situation.

CANFP offers a variety of resources for those just discovering Natural Family Planning, as well as to meet the varied needs of our CANFP Members. Most resources are available to any visitors to our site. Some resources do ask you to register as a site user in order to access them, others are available only to CANFP Members.

CANFP statewide conferences, regional events offered in collaboration with local partners, events featuring CANFP speakers, or exhbit, as well as other events throughout the state of interest to our NFP community.  Come meet one of our experts at one of these events or book a speaker for your own upcoming event.

CANFP depends on the gifts, talents, and generosity of our members and supporters. The success of our mission depends on the collaboration of our members. Please consider contributing your time treasure and talent through CANFP to share the good news of NFP with the world! Both volunteer and contracted positions available.

Stay informed by joining our email list

* indicates required
Which role(s) best describes you?