Too Much Progesterone?
Question
I am currently in my 6th week of pregnancy (last period 3/19). We saw a fertility specialist and used Gonal F with my last pregnancy and was supplemented with progesterone suppositories, oral, and eventually injections with that pregnancy which turned out great.
We got pregnant on our own this time. My OB has been monitoring my hcg and prog. levels 2x/week for the last two weeks due to my history of a miscarriage and having fertility issues in the past. Hcg is now up to 2633. My progesterone levels started @ 25 and then dropped to 20.4 three days later. I was concerned that it would continue to drop since I had that problem with my last pregnancy so I was put on Prometrium 200mg BID. It then jumped to 526. Prometrium was decreased and two days later it is 150.
My questions are: 1) Is it normal for Progesterone levels to jump that high? 2) Will this high level do any harm to the fetus? Thanks
Kris
Answer
Last Updated: November 18, 2021
According to the research of Thomas Hilgers, M.D., supplementing progesterone with Prometrium is not harmful in pregnancy. Although we generally check trough (low point) levels 1 day after the last Prometrium dose, I am surprised that your levels got so high.
I would recommend a trough level as described above. If that level is less than 25 then you should definitely continue supplementation.
In health,
George Delgado, M.D., F.A.A.F.P. Culture of Life Family Health Car
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