Sometimes Lupron can take more than one month to work, so I would be patient. If it works at shrinking your fibroids, you can consider taking it six months rather than three. However, the Lupron will not be a permanent treatment for you if you are only 38. Your periods will eventually come back and the fibroids may grow again.
There are some non-surgical treatments for your fibroids you might consider, depending on the size of your fibroids. One is uterine artery embolization, during which a radiologist specially trained in this procedure puts a catheter in an artery in your groin, threads it up to the blood supply to the fibroids, and puts beads in the fibroids’ blood supply, which results in the fibroids shrinking. This treatment is suitable if you have had all the children you want to have.
Another newer option that will likely be approved by the FDA later this year is MRI-guided ultrasound shrinkage of fibroids. With this procedure, which sometimes has to be repeated, ultrasound waves are used to “zap” fibroids and shrink them. Given your history, you might seek out a large medical center where these newer therapies are used. Because you had such serious problems with surgery in the past, your insurance company might be willing to pay for an experimental therapy.
Here is a link that describes the MRI-guided ultrasound:
http://www.cbsnews.com/stories/2005/08/01/earlyshow/contributors/emilysenay/main712982.shtml It is possible this therapy will come to a medical center in your area. Using the Lupron might buy you some time to search out suitable treatment.
Good luck!
Mary Davenport, MD