History of Pregnancy Loss

Question

Hello there,
Three and four years ago I was diagnosed with partial molar pregnancy, fortunately all my levels and follow up went fine for the whole year. After that I had a full term pregnancy (no problems at all).  But right now I am dealing with a blighted ovum.

So my question is, since all the losses were related to the same partner (husband), is there still any possibility of me being immunologic incompatible with him?

I am from Brazil and here we had this test called “cross match” done to see if we were compatible to each other, and the results come saying that we weren’t compatible and I was supposed to take some shots from his blood. But unfortunately we didn’t have the money for that and we didn’t do it, so we tried once again without even doing anything different and happily I could carry my daughter full term. So I would like to know about this issue right now since I’ve just faced a blighted ovum last week and I was wondering if is there any possibility for me being still incompatible, even after having a healthy pregnancy? Thank you for your attention.

Carol

Answer

Last Updated: July 12, 2013
Dear Carol:

Unfortunately you have presented a very interesting history. I am very happy for the blessings of the children you have been able to carry to term. From your description, it sounds as if you had two molar pregnancies, then a full term pregnancy, and now a blighted ovum.

While I am not fully familiar with the cross check you had, I think it would indicate that you fall into a general category of having sperm antibodies. The person who gave you the test was proposing that the molar and blighted ovums were part of an “allergic” reaction to your husband.

This is a fairly new and rapidly developing area of obstetrics. I do know that through NaPro Technology (from research at Pope Paul VI Institute, Omaha, NE) some physicians are having success with treating the husbands with a short term of prednisone. This apparently is reducing whatever is causing the antibody production in the wife.

Fertility difficulties are often times mixed meaning that both the wife and husband have underlying processes that need to be corrected. Therefore, I would propose that you would be taught how to chart your cycles so that the cervical mucus, the phases of the cycle, and appropriate lab and ultrasound testing could be performed. Perhaps hormone replacement or other appropriate medications could be used. All of this is morally acceptable to people of all religious and cultural backgrounds.

Of course, your husband should be examined and a sperm analysis performed to see if there is a disproportionate amount of abnormal sperm, etc. This can easily be done by working with his doctor and the laboratory ahead of time. I recommend a perforated condom which allows some sperm to pass through during a normal act of intercourse, but enough is retained to be analyzed.

I fear that I have not been very much help. However, there are a lot of resources through CANFP from which you can receive help. The first on the list would be to find a certified teacher to teach you to chart your cycles. Also, CANFP has a list of doctors in California that may be near you to help with some of the exams and appropriate testing. I wish you and your family the best outcome!

Gretchen Marsh, D.O.

Answered By:

Gretchen Marsh, D.O.
Dr. Marsh graduated from Western University of Health Sciences in 1987 in Pomona, CA and is board certified in Family Medicine by the American Osteopathic Board of Family Physicians. She has been certified as a NaProTechnology® Medical Consultant (NaPro) and Creighton model Fertility Care System (CrMS) teacher since 2001. She and her husband, Jon, have 5 sons and live in the Reno region, where she sees patients in person, in addition to her telehealth services offered via MyCatholicDoctor.com

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