Regret Yesterday’s Depo Injection


Hi, I had a question. I just received my first shot and last shot of Depo-Provera yesterday afternoon, and I read up on it all night last night. Nobody at the doctor’s visit told me of any of the side effects while being on this. I know that I’m not going to be able to get it out of my system overnight but I want to do something to speed up the process.
I’m already taking hair, skin, and nail vitamins but I’m going to up the dosage to two pills a day, plus I’m going to take calcium supplements because of the loss in bone density, drink the recommended glasses of water and exercise about an hour a day – alternating between cardio and muscle conditioning workouts. Then I might even go to saunas and take herbal supplements or herbal teas as well.

Do you think it might be too early, doing all of this? I just want to get this shot out as much as I can during the next three months so that everything can go back to normal. Should I wait and do this after? Is there anything else I can do in addition to my planned routine? What about acupuncture? What about using a natural progesterone to counteract the effect or anything else??

Is there any way I can have a test to detect how much Depo-Provera is in my system? If I want to try and conceive after taking Depo-Provera and being off it for six months to a year, what should my hormone levels be? What does Depo- Provera do to the hormones in the body?



Last Updated: January 31, 2022
Dear Jerika:

Sadly, many women report that they were not told of the side effects of Depo-Provera (medroxyprogesterone) or other contraceptives for that matter. One shot of Depo-Provera can give prolonged, detrimental effects on your health including fertility. It will take maybe six to eight months to clear and restore normal hormone levels. However, there have been many women who have reported prolonged intervals before they were able to conceive. Bone loss has been associated with prolonged use of Depo-Provera especially after two years of use. However, bone density returns to normal after a couple of years off of the Depo.

Unfortunately, women report a host of other side effects that they attribute to the shot. They include weight gain, headaches, irregular spotting and bleeding, loss of sex drive, among others. Simply “google” depo provera and one can find reports by consumers. Additionally, women report deliberate concealment of information by clinics of what they are receiving. One incident that illustrates this is of a woman with three children at a county health clinic. The children were there for their immunizations. The “nurse” attempted to give a shot to the mother without informing her that it really was depo provera and not an immunization. The thought was that women need to be chemically sterilized like an animal.

The larger question is why women want or are convinced to use Depo-Provera or any other contraceptives in the first place. Yes, women are trying to avoid a pregnancy. However, why are they putting themselves at risk for health problems and masking underlying disease that some of these contraceptives purport to “treat?” These contraceptives do nothing to help fix problems but only mask the underlying disorder.

There is a much healthier way to manage your fertility, promote healthy self respect, and learn about the sources of gynecological dysfunction. This is done with Natural Family Planning(NFP).

A certified NFP teacher will teach you how to chart the medically significant biological signs of your cycle. The chart is invaluable to physicians in helping to diagnose where problems may be. Also, you get an accurate picture of when you are fertile and infertile. NFP educates women about their bodies, puts them in the driver’s seat of their health care, and advances respect for themselves and others. Couples who use NFP have an extremely low divorce rate providing the stable environment that children deserve.

CANFP can help you locate a certified NFP teacher in your area so you can get started even while you are waiting for the Depo to wear off. I hope that this helps!


Gretchen V. Marsh, D.O.

Answered By:

Gretchen Marsh, D.O.
Dr. Marsh graduated from Western University of Health Sciences in 1987 in Pomona, CA and is board certified in Family Medicine by the American Osteopathic Board of Family Physicians. She has been certified as a NaProTechnology® Medical Consultant (NaPro) and Creighton model Fertility Care System (CrMS) teacher since 2001. She and her husband, Jon, have 5 sons and live in the Reno region, where she sees patients in person, in addition to her telehealth services offered via

Read more related questions

If I Missed a Shot Could I Get Pregnant?

I didn’t go for my injection the 4th of May. Is it possible for me to get pregnant?

The Pill: Class One Carcinogen

Ever since I heard that the birth control pill and other contraceptives were declared Level One carcinogens by the WHO at the “Spirit and Law…

The Pill to Regulate Cycles—Why Not?

I’ve had irregular periods all my life. I went to several doctors who only told me to wait it out for a couple of years…

What to Expect After 24 Years on the Pill

I am a 42 year old female and I have been on birth control since I was 18 years old. I recently stopped taking them…

How Long to Get Back to Normal After Stopping the Pill

I was just wondering what are the normal processes after coming off the pill? I decided to come off the pill because I was getting…

Post Pill and Unexplained Weight Gain

I went off the birth control pill in April, five months ago. I had been on the pill since I was 15 years old. I…

Is Tubal Ligation Indicated

I am 28 years old and pregnant with my 4th child. I have chronic kidney stones and currently have one 1 cm in my right…

Birth Control Pill Rollercoaster

I have looked at the question(s) regarding stopping BCP and the side effects, but I guess my worries aren’t about the ovulation, but rather the…

No Birth Control Pill Has Worked For Me

I have been on birth control since I was like 16. Every birth control I have been on, works for like a month and then…

Worried About Long Term Effects of My Birth Control

I am 18 years of age and just recently started having sex. My boyfriend and I came to a consensus that I start the Pill.…

Disagree on Vasectomy

I am a 36 year old mother of four children, ages 12, 8, 5 and 18 months. My husband and I have been married for…

Regret Yesterday’s Depo Injection

Hi, I had a question. I just received my first shot and last shot of Depo-Provera yesterday afternoon, and I read up on it all…

Create An Account

This is not a membership, this is an account for our CANFP website. If you decide you would like to sign up for one of our memberships later, you can do so with or without this account.

First Name *
Last Name *
E-mail *
Username *
Password *
Confirm Password *
Edit Profile
Order History
Shipping and Billing
Login Information
Notification Settings
Notification Subscriptions

CANFP conducts varied outreach programs to the community at large, in addition to serving our members (NFP users, teachers, and advocates).

CANFP provides education programs tailored to the audience, not only on Natural Family Planning, but on the wide variety of topics related to it.

Programs can be continuing education for NFP Professionals, introductory information for a lay audience of youth or adults new to the topic, or specifically tailored to the interests of a professional audience, such as educators, physicians, or clergy. Content is faith based or secular, whichever is suitable for situation.

CANFP offers a variety of resources for those just discovering Natural Family Planning, as well as to meet the varied needs of our CANFP Members. Most resources are available to any visitors to our site. Some resources do ask you to register as a site user in order to access them, others are available only to CANFP Members.

CANFP statewide conferences, regional events offered in collaboration with local partners, events featuring CANFP speakers, or exhbit, as well as other events throughout the state of interest to our NFP community.  Come meet one of our experts at one of these events or book a speaker for your own upcoming event.

CANFP depends on the gifts, talents, and generosity of our members and supporters. The success of our mission depends on the collaboration of our members. Please consider contributing your time treasure and talent through CANFP to share the good news of NFP with the world! Both volunteer and contracted positions available.

Stay informed by joining our email list

* indicates required
Which role(s) best describes you?