Timing of Prometrium

Question

I am 31 years old and really want a child.  I have always had irregular periods since as a teenager. For the past 3 years I did not menstruate without the use of provera.  I have been on clomid for 4 months.  Each time I have ovulated on a dose of 100 mg but no success of pregnancy.  This month my doctor prescribed taking prometrium 200 mgs vaginally beginning the 14th day of my cycle.  I have a 34 day cycle and ovulate between day 17-19.  Will this affect my chances of getting pregnant?  Will it affect the production of fertile cervical mucus?  Please help…

Answer

Prometrium is a form of natural progesterone, and must be given cooperatively in the cycle. In other words, it is given AFTER ovulation, at the time the levels would naturally increase. If you are charting your fertility, you would time the progesterone to be given cooperatively three days after ovulation (as determined by charting the peak day or by ovulation kits) through twelve days after ovulation.

If you are ovulating between days 17-19, which does make sense if you are having a 34 day cycle, day 14 is too early to begin supplementing with progesterone, and if begun too early progesterone supplementation may have an adverse effect on mucus and actually impair ovulation.

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